Big Beef is a good hybrid to use as long as you don't have that third race of fusarium wilt. I guess the best way to find out is plant a bunch of Big Beefs and if they all stay fusarium free then you don't have to worry for now.
As to using the seed from Big Beefs I have done that and the resulting tomato plants were not always as good nor as disease resistant so you should talk to someone who knows more about that type of thing than I do.
Bill
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