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Old March 29, 2018   #4
crmauch
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Join Date: May 2013
Location: Honey Brook, PA Zone 6b
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I would say if you know specifically what you are breeding for, it would be better to start with stable varieties that have the genetics you're looking for. If you want to combine multiple varieties and see if any thing interesting comes out, then I think breeding with the F2 or F3 is quite fine.

Another difference would be that when crossing stable varieties you would start with a small F1 generation (the seeds of your cross) and then plant larger amounts of F2 and start selecting there.

If you are crossing unstable varieties, you'd want to plant far more seeds of your initial cross (your F1) and start selecting in that generation.
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