Bower,
I don't know if the "disease" can be passed internally or externally with the seed. If it is carried on the seed and is indeed a pathogen, the bleach cleansing method I believe Carolyn used to use should kill it. If internal, there probably is nothing you can do.
I have experienced damage to branches in the past from different tieing methods which resulted in a type of necroses which looked like a disease but wasn't.
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