Bill - I'm sorry for your plant's problems but are you saying that if you had only aggressively pruned your plants none of these problems would have developed? If so I'd have to strongly disagree.
Pruning isn't the cause for bad weather, aphids and whiteflies, Early Blight, grey mold and other spot diseases. Those issues could care less whether a plant has been aggressively pruned or not. They will go after single stem plants as much as they will any unpruned plant. So given the right conditions they grab it. Given even marginal controlled condition, they move on.
Not that placing blame is important, especially after the fact. But if one insists on blaming something, pruning or the lack of it isn't the issue.
Weather we can't control of course except in a greenhouse, aphids and whiteflies we can control with decreased use of N and a garden hose and mild pesticides if necessary with careful monitoring and quick intervention when needed, and disease prevention and control has its tools as well but it is up to us to use them and use them correctly.
We do that and our reward is all the fruit we wouldn't have gotten if we had aggressively pruned the plant.
Dave