I don't know about "best," but what I use is my own homemade compost, a handful of alfalfa pellets in the bottom of the hole when I plant my tomatoes, a tablespoon of a humic acid product, and occasionally water with some liquid seaweed (capful in a gallon of water) or homemade nettle tea or comfrey tea.
And mulch!
For new garden sites, I've used free coffee grounds as well as lots of compost.
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