I have observed hybrid vigor in the tomato crosses I have made. The F1s have been measurably more vigorous than either parent in most cases. I'm a believer.
With regard to potential genetic bottlenecking, I'm not concerned hugely about saving seeds from limited numbers of sibling plants because through selection of the better examples among the siblings, I have observed improved performance in the following generations. I'm thinking since tomatoes are 95% self-pollinating naturally, some degree of "bottlenecking" would occur with or without human interference.
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